Google is starting to use real-time search results, including Twitter tweets relevant to search words, which means your tweets could show up on the first page of the search engine results page (SERP)! You can see this in the screen shot of a Google search on “iPad.” The tweets themselves are indexed, and the first 40 or so characters of your Tweet (depending on how long your username is) will make up the title tag when your tweet shows up on Google search results, so choose the first two or three words of a tweet carefully, including at least one important keyword for your website.
In your profile, make sure there’s a link to your actual website, not just your Facebook or MySpace page. Use your profile’s bio line, which is 160 characters, to your best advantage by making it relevant to your website and using keywords. Your bio is indexed, and what’s in your bio is what will or won’t give your Twitter profile its relevance. Additionally, your Twitter bio is your meta description, so make it count.
When you develop followers, don’t abandon them. Make sure to engage them and don’t just use your tweets to constantly push your products on people.